Table 2. Recommended intervals between IG treatment and measles or varicella vaccine [9,10]

Indications and blood products	Recommended intervals (usual dose)
IVIG
Primary immunodeficiency disorders  Measles or varicella prophylaxis  Immune thrombocytopenic purpura  Kawasaki disease	8 mon (300–400 mg IgG/kg)8 mon (400 mg IgG/kg)10 mon (1,000 mg IgG/kg)11 mon (2,000 mg IgG/kg)
Blood transfusion
RBCs, washed  RBCs, adenine-saline added  Packed RBCs (hematocrit 65%)  Whole blood (hematocrit 35%–50%)  Plasma or platelet products	0 mon (10 mL/kg; negligible IgG)3 mon (10 mL/kg; 10 mg IgG/kg)6 mon (10 mL/kg; 60 mg IgG/kg)6 mon (10 mL/kg; 80–100 mg IgG/kg)7 mon (10 mL/kg; 160 mg IgG/kg)
Intramuscular IG
Hepatitis A, contact prophylaxis  Hepatitis A, international travel  Measles prophylaxis	3 mon (0.1 mL/kg; 3.3 mg IgG/kg)3 mon (0.2 mL/kg; 10 mg IgG/kg)6 mon (0.5 mL/kg; 80 mg IgG/kg)
Specific IG
Tetanus IG (TIG)1)  Hepatitis B IG (HBIG)1)  Rabies IG (RIG)1)  Varicella IG (VIG)1)  Cytomegalovirus IG2)  Botulinum IG2)	3 mon (250 U; 10 mg IgG/kg)3 mon (0.06 mL/kg; 10 mg IgG/kg)4 mon (20 U; 22 mg IgG/kg)5 mon (125 U; 60 mg IgG/kg)6 mon (150 mg IgG/kg)6 mon (1 mL/kg; 160 mg IgG/kg)

Intramuscular injection,
Intravenous injection.
IG: immunoglobulin; IVIG: intravenous immunoglobulin; IgG: immunoglobulin G; RBC: red blood cell; HBIG: hepatitis B immunoglobin.