Table 2. Clinical characteristics and organ involvement of MIS-C with or without hyperferritinemia

MIS-C with hyperferritinemia (n = 11) MIS-C without hyperferritinemia (n = 11) P value
Clinical
 Age, year 9.1 (4.1–16.0) 9.5 (0.9–12.0) 0.669
 Male sex 5 (45.5) 6 (54.5) 0.670
 Length of hospital stays, day 10.0 (5.0–18.0) 6.0 (4.0–15.0) 0.072
 Fever duration, day 5.0 (3.0–15.0) 5.0 (3.0–10.0) 0.917
 Skin rash 7 (63.6) 10 (90.9) 0.311
 Met KD criteria 10 (90.9) 9 (81.8) 1.000
 Complete KD 6 (54.5) 5 (45.5) 1.000
Organ involvement (see Table 1)
 Cardiac involvement 8 (72.7) 4 (36.4) 0.198
 Mucocutaneous involvement 11 (100.0) 10 (90.9) 1.000
 Shock 6 (54.5) 0 (0.0) 0.012
 Gastrointestinal involvement 11 (100.0) 9 (81.8) 0.476
 Hematologic involvement 10 (90.9) 7 (63.6) 0.311
 Others: respiratory, neurologic, or renal1) 8 (72.7) 6 (54.5) 0.659
 Number of organs involved 4.0 (2.0–5.0) 3.0 (2.0–4.0) 0.002
Data are presented as frequency (%) or median (range). MIS-C: multisystem inflammatory syndrome in children; KD: Kawasaki disease.
The Council of State and Territorial Epidemiologists/Centers for Disease Control and Disease Prevention (CSTE/CDC) case definition includes five types of organ involvement (i.e., cardiac, mucocutaneous, shock, gastrointestinal, and hematologic). Other organ dysfunction (e.g., respiratory, neurologic, renal, or musculoskeletal) is not included in the CSTE/CSC case definition.